Major Symposia

Peripheral Neuroimmune Interactions

Chairs

• Daniel Mucida, HHMI, Rockefeller Univ.
• Esther Borges Florsheim, Arizona State Univ.

Speakers

• Daniel Mucida, HHMI, Rockefeller Univ., Neuro-immune interactions in the gut
• Esther Borges Florsheim, Arizona State Univ., Mast cell-derived lipid mediator promotes food aversion
• Caroline L. Sokol, Massachusetts Gen. Hosp., Neuroimmune circuits drive allergic immunity
• Jessica A. Osterhout, Univ. of Utah, Neural circuits of sickness behavior
• Felipe Almeida de Pinho Ribeiro, Washington Univ. Sch. of Med. in St. Louis, Sensory control of immunity

Cell Death and Immunity: Caspases and Beyond

Chairs

• Francis K. Chan, Duke Univ.
• Sunny Shin, Univ. of Pennsylvania Perelman Sch. of Med.

Speakers

• Sunny Shin, Univ. of Pennsylvania Perelman Sch. of Med., Inflammasome-mediated anti-bacterial defense
• Megan H. Orzalli, Univ. of Massachusetts Chan Med. Sch., Activation and inhibition of cutaneous antiviral immunity
• Julie Magarian Blander, Weill Cornell Med., Phagocytic mode of non-canonical NLRP3 inflammasome activation: implications to pyroptosis and immunity
• Francis K. Chan, Duke Univ., Necroptosis in anti-viral immunity and tumor immunotherapy
• Weiping Zou, Univ. of Michigan, Ferroptosis in tumor immunity
• Kodi S. Ravichandran, Washington Univ. Sch. of Med. in St. Louis, Eating lessons from phagocytes and the implications to immunity

Generously supported by PerkinElmer Health Sciences, Inc. & Honeycomb Biotechnologies

Mechanisms of Innate Immune Memory and Tissue Adaptation

Chairs

• Shruti Naik, New York Univ. Grossman Sch. of Med.
• Joseph C. Sun, Mem. Sloan Kettering Cancer Ctr.

Speakers

• Ruslan Medzhitov, HHMI, Yale Sch. of Med., Tissue homeostasis and inflammation
• Luis B. Barreiro, Univ. of Chicago, Genetic and epigenetic determinants of inter-individual variation in innate immune responses to infectious agents
• Timothy E. O’Sullivan, Univ. of California, Los Angeles, Transcriptional and epigenetic control of natural killer cell memory
• Ai Ing Lim, Princeton Univ., Pre-birth immune education
• Steven Z. Josefowicz, Weill Cornell Med., Epigenetic memory of inflammation and infection in hematopoietic progenitor cells
• Shruti Naik, New York Univ. Grossman Sch. of Med., Adaptive and maladaptive immune-epithelial interactions

Aging, Obesity, and Adverse Immune Responses

Chairs

• Lydia Lynch, Brigham and Women’s Hosp.
• Andrew E. Hogan, Maynooth Univ., Ireland

Speakers

• Lydia Lynch, Brigham and Women’s Hosp., Uncoupling the effects of obesity from dietary lipids on cancer development
• Andrew E. Hogan, Maynooth Univ., Ireland, MAITabolism: Unravelling the impact of obesity on human MAIT cells and their contribution to disease
• Semir Beyaz, Cold Spring Harbor Lab., Dietary regulation of stem cell—immune cell—microbiome interactions that influence cancer
• Susan M. Kaech, Salk Inst. for Bio. Sts., You are what you eat: nutrient preferences by effector and exhausted T cells
• Alison E. Ringel, Ragon Inst. of MGH, MIT and Harvard, Aging and immunity in the tumor niche

Engineering at the Interface of Immunology and Immunotherapy

Chairs

• Jeffrey A. Hubbell, Univ. of Chicago
• Susan N. Thomas, Georgia Tech

Speakers

• Jeffrey A. Hubbell, Univ. of Chicago, Engineering cytokines to modulate regiospecific function
• Evan A. Scott, Northwestern Univ., Engineering synthetic nanocarriers for targeted immune modulation
• Jennifer H. Elisseeff, Johns Hopkins Univ., Engineering immune-stromal crosstalk regulating tissue structure
• Sai T. Reddy, Swiss Fed. Inst. of Tech., Zurich, Synthetic coevolution of neutralizing antibodies and SARS-CoV-2
• James J. Moon, Univ. of Michigan, Engineering strategies to modulate the gut microbiome and immune system
• Susan N. Thomas, Georgia Tech, Engineered lymph node drug delivery and disease modeling technologies enable next-generation approaches in cancer immunotherapy

Environmental Drivers of Myeloid Cells

Chairs

• Jessica A. Hamerman, Benaroya Res. Inst.
• P’ng Loke, NIAID, NIH

Speakers

• Jessica A. Hamerman, Benaroya Res. Inst., Monocyte differentiation during inflammation
• P’ng Loke, NIAID, NIH, Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation
• Paul Kubes, Univ. of Calgary, Loss of resident macrophage identity induced by local environmental changes
• Mark B. Headley II, Fred Hutch Cancer Res. Ctr., Immunosurveillance of the lung by specialized dendritic cell populations
• Amariliz Rivera, Rutgers New Jersey Med. Sch., Novel insights on the role of interferons as regulators of pulmonary antifungal immunity

Mucosal Immunity in Health and Disease

Chairs

• Ivaylo I. Ivanov, Columbia Univ.
• Manuela Raffatellu, Univ. of California, San Diego

Speakers

• Kathy D. McCoy, Univ. of Calgary, Microbes and metabolites: shaping mucosal immunity
• Isaac M. Chiu, Harvard Med. Sch., Nociceptor neuron regulation of gut barrier function and immunity
• Manuela Raffatellu, Univ. of California, San Diego, New insights on mucosal immunity to Enterobacteriaceae
• Ivaylo I. Ivanov, Columbia Univ., Homeostatic functions of commensal Th17 cells
• Suzanne Devkota, Cedars-Sinai Med. Ctr., Immunological and physiological responses to gut bacterial translocation in humans
• Dan R. Littman, New York Univ. Grossman Sch. of Med., Microbiota guidance of T cell differentiation

Immunity to Emerging Pathogens: COVID-19 and Beyond

Chairs

• James E. Crowe Jr., Vanderbilt Univ. Med. Ctr.
• Laura M. Walker, Moderna

Speakers

• James E. Crowe Jr., Vanderbilt Univ. Med. Ctr., Human monoclonal antibodies for emerging infections
• Laura M. Walker, Moderna, Evolution of antibody immunity following Omicron breakthrough infection
• Robert A. Seder, NIAID, NIH, Scientific and clinical development of monoclonal antibodies to prevent malaria
• Mark T. Esser, AstraZeneca, From the lab to the jab: lessons learned from the development of AstraZeneca’s long-acting antibody combination (Evusheld) for the prevention and treatment of COVID-19
• Amy L. Hartman, Univ. of Pittsburgh, Combating the threat of Rift Valley fever virus infection in utero