Friday, May 12, 2023 8:00 AM – 10:00 AM ET Room 207B
Block Symposium
Transplant Immunology: from Alloreactivity to Immunoregulation
Chairs
- Jonathan Bromberg, Univ. of Maryland, Baltimore
- Maria-Luisa Alegre, Univ. of Chicago
Speakers
- Julia Miranda R. Bazzano, Emory Univ., Gm2a as a novel regulator of CD8+ T cell threshold of activation in transplantation
- Erik H. Koritzinsky, Cleveland Clin. Lerner Res. Inst., Allograft TLR9 is required for endogenous donor-reactive memory CD8 T cell activation to mediate CTLA-4Ig resistant rejection of high-risk cardiac allografts
- Michael Nicosia, Cleveland Clin. Fndn., Water channel Aquaporin 4 is required for T cell activation
- Jennifer Brianne Allocco, Univ. of Chicago, Variegated levels of alloreactive T cell dysfunction in transplantation tolerance determine graft vulnerability to infection-triggered rejection
- Giorgio Raimondi, Johns Hopkins Sch. of Med., Solid organ and vascularized composite allotransplantation have distinct requirements for localized delivery of enhanced costimulation blockade to control rejection
- Young S. Lee, Univ. of Maryland Sch. of Med., Purine metabolic pathway regulates regulatory T cell stability and function
- Ping Zhang, Fred Hutchinson Cancer Res. Ctr., Type-1 regulatory T cells are critical for curative immunotherapy outcomes
- Jemma H. Larson, Univ. of Minnesota, Human CAR19 CD8+ iTreg exceed CAR19 CD8 CTLs both in suppressing GVHD lethality and eliminating CD19+ Nalm-6 lymphoma cells in vivo
