Saturday, May 13, 2023     10:15 AM – 12:15 PM ET     Room 207A

Block Symposium

Wasting Thyme: Thymus Function in Health and Disease

Chairs

• Jarrod A. Dudakov, Fred Hutchinson Cancer Res. Ctr.
• Mercedes Rincon, Univ. of Colorado

Speakers

• Lauren Ilyse Richie Ehrlich, Univ. of Texas, Austin, CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance
• Chloe Houques, IGMM, Thymic innate lymphoid cells promote thymocyte differentiation of transplanted hematopoietic progenitors in immunodeficient mice
• Felipe Pereira, Univ. of Colorado Anschutz Med. Campus, Inactivation of GSK3β by Ser³⁸⁹ phosphorylation prevents thymocyte necroptosis and impacts Tcrβ and Tcrα repertoire diversity
• Yong Fan, Allegheny Singer Res. Inst., Tissue engineering human thymus from iPSCs to support human T cell development
• Menglin Jiang, St. Jude Children's Res. Hosp., Genetic tracing of thymic T cell differentiation
• Sarah A. Wedemeyer, Unversity of Texas, San Antonio Hlth., Role of paracrine mTOR signaling in regulating thymus size and function
• D. Tyler Boone, Geisel Sch. of Med., Dartmouth Col., NDRG3 is a novel regulator of T and B cell development with phosphorylation-specific activity and phenotypes
• Shil Patel, NCI, NIH, Harnessing spatial transcriptomics to study fate decisions and lineage specification in T cell development