Saturday, May 13, 2023     12:30 PM – 2:30 PM ET     Room 102AB

Block Symposium

Molecular Mechanisms of Cytokine Function

Chairs

• Ken J. Oestreich, Ohio State Univ. Col. of Med.
• Warren Leonard, NHLBI, NIH

Speakers

• Suyasha Roy, NHLBI, NIH, Blimp-1 is a negative regulator of IL-2 signaling in T cells
• Hiroyuki Nagashima, NIAMS, NIH, Distinct 3D remodeling of Il4-Il13-Il5 loci mediates differential type 2 responses in innate versus adaptive lymphocytes
• Melissa Leonard, Ohio State Univ. Col. of Med., The Ikaros zinc finger transcription factor Aiolos as a novel regulator of T cell migration
• Cheuk Lam Cheung, Indiana Univ. Sch. of Med., Identification of a novel interleukin-9 receptor complex in non-hematopoietic cells
• Anagha Yogam , NCI, NIH, Bottoms up!: inferring relevant immune phenotypes from bulk cytokine kinetics via semi-supervised machine learning
• Ang Cui , Broad Inst. of MIT and Harvard, Dictionary of immune responses to 86 cytokines in vivo at single-cell resolution
• Satya Singh, NIAID, NIH, Human CCR6⁺ Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity
• Rachael Laura Philips, NIAMS, NIH, STAT1 gain of function mutation impairs immune response to viral infections