Saturday, May 13, 2023 3:45 PM – 5:45 PM ET Room 204ABC
Block Symposium
Innate Immune Signal Transduction Pathways during Infection
Chairs
- Sunny Shin, Perelman Sch. of Med., Univ. of Pennsylvania
- Jonathan Kagan, Boston Children's Hosp. and Harvard Med. Sch.
Speakers
- Neha Dubey, Washington Univ. Sch. of Med. in St Louis , Mycobacterium tuberculosis exploits FIP200 regulated cell-death pathways to promote replication
- Alexander Rapp, Geisel Sch. of Med., Dartmouth Col., Uncovering alterations in the murine interferon response due to dsRNA mycovirus during Aspergillus fumigatus infection
- Lynn Soong, Univ. of Texas Med. Br. at Galveston, Syk-dependent responses and Innate cytosolic defenses in Orientia tsutsugamushi-infected macrophages
- Reena Agrawal-Rajput, Indian Inst. of Adv. Res., Chlamydia trachomatis infection renders M2 generation to mediated immunosuppression
- Alex A. Compton, NCI, NIH, The extracellular tail of IFITM3 promotes SARS-CoV-2 entry into cells and is diversifying in primates
- Cheyanne Foster, Case Western Reserve Univ., Double DAMPs—NLRP3 priming of murine bone marrow derived mast cells with IL-33 leads to robust IL-1β secretion in a Gasdermin-D independent manner
- Thu R. Nguyen, Case Western Reserve Univ., Murine eosinophils release IL-1β via a non-lytic mechanism dependent on gasdermin D (GSDMD) expression but independent of GSDMD proteolytic processing
- George R. Dubyak, Case Western Reserve Univ., Lyososome membrane permeabilization induces plasma membrane macropores to activate K+-efflux-dependent NLRP3 inflammasomes in murine dendritic cells
