Sunday, May 14, 2023     3:45 PM – 5:45 PM ET     Room 207B

Block Symposium

Environmental Influences: Sex, Pregnancy, Diet, and T Cells

Chairs

• Robert B. Lochhead, Med. Col. of Wisconsin
• Wendy Goodman, Case Western Reserve Univ. Sch. of Med.

Speakers

• Sarah K. McNeer, Case Western Reserve Univ. Sch. of Med., Murine CD4⁺ T cells exhibit sexually dimorphic responses to estrogen signaling
• Farha J. Mithila, Brown Univ., Effect of estrogen signaling in CD8 T cell mediated antiviral response
• Jing Li, Stanford Univ. Sch. of Med., Regulation of fetal tolerance by KIR⁺ regulatory CD8⁺ T cells in human pregnancy
• Hee Kap Kang, Ann & Robert H. Lurie Children's Hosp. of Chicago and Northwestern Univ., Prenatally Educated Friendly NK Cells regulate Allo-specific T cell Responses through expansion of Foxp3⁺CD4⁺Treg Cells and suppression of Type 1 and 17 CD8⁺T cell responses
• Megan Mulholland, Lund Univ.. Sweden, PD1 blockade promotes IFN-γ production by progenitor exhausted PD1-expressing T cells in atherosclerotic plaques
• Brenna Appleton, Vanderbilt Univ., Oxidized phospholipid oxPAPC induces a dysfunctional Th1-like phenotype in regulatory T cells
• Haiguang Wang, Univ. of Minnesota Med. Sch., T follicular helper cells restrain obesity-related metabolic disease by damping intestinal inflammation
• Andrew R. Patterson, Vanderbilt Univ. Med. Ctr., Overlapping Mendelian disorders of immunity and metabolism shape CD4⁺ T cell immunometabolism