Sunday, May 14, 2023 3:45 PM – 5:45 PM ET Room 206
Block Symposium
Regulation of Protective T Cell Immunity in Cancer
Chairs
- Khashayarsha Khazaie, Mayo Clin.
- Troy Randall, Univ. of Alabama at Birmingham
Speakers
- Zoe C. Schmiechen, Univ. of Minnesota, Abrogating regulatory T cells overcomes tumor-specific T cell exhaustion and prevents metastatic pancreatic cancer
- David J. Friedman, Mayo Clin., The molecular underpinnings of Treg plasticity in cancer
- Qiyuan Yang, Salk Inst. for Biological Studies, PPARd restricts intratumoral Treg function through negatively regulating the CIITA-MHCII axis
- Marie Boutet, Albert Einstein Col. of Med., Loss of the MLL3 tumor suppressor accelerates breast tumor onset via HIF1a-induced CCL2-mediated recruitment of CCR2+ regulatory T cells
- Maria A. Cardenas, Emory Univ., Stem-like CD4 T differentiation controls CD8 T cell immunity or tolerance in cancer
- Lizmarie Garcia-Rivera, Salk Inst. for Biological Studies, Spatial profiling of glioblastoma microenvironments and response to immunotherapy
- Sweta Desai, Univ. of Alabama at Birmingham, Characterizing the role of IL-33/ST2 axis in regulating anti-tumor function by CD8 T cells during tumor metastasis in the omentum
- Katayoun Ayasoufi, Mayo Clin., Circulating cell-free DNA directly inhibits T cell function and contributes to peripheral immunosuppression in experimental GBM
