Friday, May 12, 2023     10:15 AM – 12:15 PM ET     Room 202B

Human Immunological Diseases and Pathologies: Current Standard of Care, Mechanisms of Action, and Unmet Needs

Sponsored by the AAI Clinical Immunology Committee

Chairs

• Erica L. Stone, GigaGen, AAI Clinical Immunology Committee Chair
• Thomas A. Wynn, Pfizer

Speakers

• Joanne L. Viney, Seismic Therapeut., New therapeutic approaches for dysregulated adaptive immunity
• John C. Cambier, Univ. of Colorado Anschutz Sch. of Med., Exploiting inverse agonism for therapy in autoimmunity: immune cell silencing without death
• Kristie M. Grebe, Anokion, Harnessing natural tolerance pathways in the liver to treat autoimmune diseases: evidence from KAN-101 for the treatment of celiac disease
• David M. Berman, ImmunoCore, TCR bispecific protein therapeutics to treat autoimmunity

This session will include talks on a variety of immune-driven disease states and describe disease pathogenesis, current treatments, and their shortfalls, where potential areas of improvement may be in new treatments, and next therapies on the horizon. Linking the bench to the clinic will be emphasized.